BDBM50444018 CHEMBL1999832

SMILES COc1cc2nc(Nc3cccc(Br)c3)nc(Nc3cccc(Br)c3)c2cc1OC

InChI Key InChIKey=RAGCBYGVDCNHLI-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50444018   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50444018(CHEMBL1999832)Copy SMILESCopy InChI

Affinity DataIC50: 670nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as Hoechst 33342 accumulation treated 30 mins before Hoechst 33342 addition measured up to...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2014
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50444018(CHEMBL1999832)Copy SMILESCopy InChI

Affinity DataIC50: 860nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as pheophorbide A accumulation treated 30 mins before pheophorbide A addition measured up ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2014
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL