BDBM50444025 CHEMBL3092487

SMILES COc1ccc(cc1OC)-c1nc(Nc2cccc(c2)C(F)(F)F)c2ccccc2n1

InChI Key InChIKey=DTISEOLQYYBKBP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50444025   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50444025(CHEMBL3092487)Copy SMILESCopy InChI

Affinity DataIC50: 240nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as pheophorbide A accumulation treated 30 mins before pheophorbide A addition measured up ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2014
Entry Details Article
Copy BDB DOIPubMed
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TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50444025(CHEMBL3092487)Copy SMILESCopy InChI

Affinity DataIC50: 300nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as Hoechst 33342 accumulation treated 30 mins before Hoechst 33342 addition measured up to...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2014
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL