BDBM50444283 CHEMBL3093638::US9649309, Compound UNC2090A

SMILES CCCCNc1ncc(C(=O)Nc2ccc(cc2)S(=O)(=O)N2CCOCC2)c(NC[C@@H]2CCCNC2)n1

InChI Key InChIKey=JGSVNIPAOGOWTI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50444283   

TargetTyrosine-protein kinase Mer(Human)
Eshelman School of Pharmacy�Department of Pharmacology�Lineberger Compreh

Curated by ChEMBL
LigandPNGBDBM50444283(CHEMBL3093638 | US9649309, Compound UNC2090A)
Affinity DataIC50: 140nMAssay Description:Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Eshelman School of Pharmacy�Department of Pharmacology�Lineberger Compreh

Curated by ChEMBL
LigandPNGBDBM50444283(CHEMBL3093638 | US9649309, Compound UNC2090A)
Affinity DataIC50: 550nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
Eshelman School of Pharmacy�Department of Pharmacology�Lineberger Compreh

Curated by ChEMBL
LigandPNGBDBM50444283(CHEMBL3093638 | US9649309, Compound UNC2090A)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Eshelman School of Pharmacy�Department of Pharmacology�Lineberger Compreh

Curated by ChEMBL
LigandPNGBDBM50444283(CHEMBL3093638 | US9649309, Compound UNC2090A)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Axl kinase (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed