BDBM50445055 CHEMBL3098744::US10195186, Example 45::US9682967, 43
SMILES CC(C)c1ccc(C(=O)Nc2cccc(C)n2)c(c1)C(O)=O
InChI Key InChIKey=KVTVWSRXECDHQR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50445055
Affinity DataKi: 190nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Affinity DataKi: 1.05E+3nM IC50: 1.10E+3nMpH: 7.4Assay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...More data for this Ligand-Target Pair