BDBM50445124 CHEMBL3103868

SMILES N[C@H]1CCCN(C1)c1ccncc1NC(=O)c1nc(ccc1N)-c1c(F)cccc1F

InChI Key InChIKey=RJBLYAOGZIACGS-ZDUSSCGKSA-N

Data  3 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50445124   

TargetSerine/threonine-protein kinase pim-1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL

LigandBDBM50445124(CHEMBL3103868)Copy SMILESCopy InChI

Affinity DataKi:  0.00200nMAssay Description:Inhibition of PIM1 (unknown origin) using Biotin-AGAGRSRHSSYPAGT-OH as substrate after 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetSerine/threonine-protein kinase pim-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL

LigandBDBM50445124(CHEMBL3103868)Copy SMILESCopy InChI

Affinity DataKi:  0.00400nMAssay Description:Inhibition of PIM2 (unknown origin) using Biotin-AGAGRSRHSSYPAGT-OH as substrate after 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
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TargetSerine/threonine-protein kinase pim-3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL

LigandBDBM50445124(CHEMBL3103868)Copy SMILESCopy InChI

Affinity DataKi:  0.00600nMAssay Description:Inhibition of PIM3 (unknown origin) using Biotin-AGAGRSRHSSYPAGT-OH as substrate after 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL