BDBM50445826 CHEMBL3105402
SMILES O=C(CCc1nc2ccccc2c(=O)[nH]1)N1CCN(CC1)C(=O)c1cccs1
InChI Key InChIKey=YMIQFFBYZDVYBQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50445826
TargetPoly [ADP-ribose] polymerase 1(Human)
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Affinity DataIC50: 9.80nMAssay Description:Inhibition of GST-tagged recombinant human PARP-1 expressed in Escherichia coli after 30 mins by fluorescence-based assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Human)
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Affinity DataEC50: 256nMAssay Description:Inhibition of PARP-1-mediated PARylation in H2O2-induced human HeLa cells preincubated for 3 hrs followed by H2O2 addition measured after 5 mins by D...More data for this Ligand-Target Pair