BDBM504462 N-(1-((1s,4s)-4-(13-((2-(2,6- dioxopiperidin-3-yl)-1,3- dioxoisoindolin-5-yl)oxy)- 2,5,8,11- tetraoxatetradecyl)cyclohexyl)- 5-(piperidin-1-ylmethyl)-1H- benzo[d]imidazol-2-yl)-3- (trifluoromethyl)benzamide::US11065231, Example 42

SMILES FC(F)(F)c1cccc(c1)C(=O)NC1Nc2cc(CN3CCCCC3)ccc2N1[C@@H]1CC[C@H](COCCOCCOCCOCCOc2ccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c3c2)CC1

InChI Key InChIKey=KAPMGVNJPHGMCR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504462   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Arvinas Operations

US Patent
LigandPNGBDBM504462(N-(1-((1s,4s)-4-(13-((2-(2,6- dioxopiperidin-3-yl)...)
Affinity DataIC50: 650nMAssay Description:A Z′-Lyte assay based on a fluorescence resonance energy transfer (FRET) readout was developed for measuring IRAK4-dependent phosphorylation of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
US Patent