BDBM50446299 CHEMBL3109328

SMILES CCCN(Cc1ccc(NC(=O)Cc2ccc(cc2)S(=O)(=O)CC)cc1)Cc1ccc(cc1)C(C)(C)C

InChI Key InChIKey=QDGJGZABKMERAG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446299   

TargetNuclear receptor ROR-gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50446299(CHEMBL3109328)
Affinity DataIC50: 40nMAssay Description:Inverse agonist activity at biotinylated human RORgammat LBD expressed in Escherichia coli BL21 assessed as inhibition of SRC1 recruitment after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50446299(CHEMBL3109328)
Affinity DataIC50: 1.00E+4nMAssay Description:Inverse agonist activity at biotinylated human RORgammat expressed in Escherichia coli BL21 assessed as effect on recruitment of SRC1/2 after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed