BDBM50446782 CHEMBL3114672

SMILES COc1cc(cc(c1O)[N+]([O-])=O)C(=O)P(O)(O)CC[C@H](N)C(O)=O

InChI Key InChIKey=VTLCVNMSKLAHKI-ZETCQYMHSA-N

Data  3 IC50  11 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50446782   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataIC50:  8.60E+3nMAssay Description:Displacement of [3H]-L-AP4 from human mGlu4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human mGlu4 receptor by FLIPR assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(RAT)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataIC50:  2.30E+6nMAssay Description:Antagonist activity at rat GluN1a/mouse GluN2B receptors expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glucine induced cu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at mGlu4 assessed as decrease in PF-induced presynaptic calcium amplitude in rat coronal slices by Fluo-4FF-AM dye based fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Mus musculus)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  200nMAssay Description:Agonist activity at mGlu4 in C57/Bl6 mouse GP neurons assessed as inhibition of striatopallidal GABAergic inhibitory postsynaptic current amplitude b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  5.30E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  900nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  6.60E+4nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataIC50:  1.10E+6nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  1.94E+4nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  1.01E+5nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed