BDBM50446871 CHEMBL3115112

SMILES COC1COCCC1N[C@@H]1C[C@H]2CNC[C@]2(C1)C(=O)N1CCc2ncc(cc2C1)C(F)(F)F

InChI Key InChIKey=JUMFLEBVAOKXJD-KNGZZHKESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446871   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446871(CHEMBL3115112)
Affinity DataIC50:  780nMAssay Description:Binding affinity to CCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446871(CHEMBL3115112)
Affinity DataIC50:  770nMAssay Description:Antagonist activity at CCR2 receptor in human THP1 cells assessed as inhibition of MCP-1 induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed