BDBM50446993 CHEMBL3116052

SMILES C[C@H](Nc1nc(Nc2cn(C)cn2)c2ccn(C3CC3)c2n1)c1ncc(F)cn1

InChI Key InChIKey=MXIBMXWJAOYHPZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50446993   

TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50446993(CHEMBL3116052)
Affinity DataIC50: 27nMAssay Description:Inhibition of Jak2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50446993(CHEMBL3116052)
Affinity DataIC50: 29nMAssay Description:Inhibition of Jak1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50446993(CHEMBL3116052)
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of Jak3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed