BDBM50447176 CHEMBL3113166::US10752581, Compound 36
SMILES COc1cccc(CNc2ccc(cc2)S(=O)(=O)Nc2nc3ccccc3o2)c1O
InChI Key InChIKey=PLLGXMASDDMGST-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50447176
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataKi: 530nMAssay Description:Uncompetitive inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate assessed as 12-HPETE formation by Henri-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataKi: 620nMAssay Description:Competitive inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate assessed as 12-HPETE formation by Henri-Mi...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged human reticulocyte 15-LOX1 using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged human epithelial 15-LOX2 using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair