BDBM50447216 CHEMBL3113176::US10752581, Compound 46

SMILES COc1cccc(CNc2ccc(cc2)S(=O)(=O)Nc2cnc3ccccc3c2)c1O

InChI Key InChIKey=BKYJEYMZCAWAPA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447216   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
Eastern Virginia Medical School

US Patent
LigandPNGBDBM50447216(CHEMBL3113176 | US10752581, Compound 46)
Affinity DataIC50:  480nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
Eastern Virginia Medical School

US Patent
LigandPNGBDBM50447216(CHEMBL3113176 | US10752581, Compound 46)
Affinity DataIC50:  480nMAssay Description:Inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed