BDBM50447377 CHEMBL3114701

SMILES CC1CCN(C\C=C\C(=O)N2CCOc3cc4ncnc(Nc5cccc(c5)C#C)c4cc23)CC1

InChI Key InChIKey=OWUREEFSSOCYKL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447377   

TargetEpidermal growth factor receptor(Human)
Jiangsu Aosaikang Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447377(CHEMBL3114701)
Affinity DataIC50: 5nMAssay Description:Inhibition of EGFR (unknown origin) after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangsu Aosaikang Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447377(CHEMBL3114701)
Affinity DataIC50: 82nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR in human KB cells incubated for 1 hr prior to EGF challenge measured after 6 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed