BDBM50447379 CHEMBL3114699

SMILES O=C(\C=C\CN1CCOCC1)N1CCOc2cc3ncnc(Nc4cccc(c4)C#C)c3cc12

InChI Key InChIKey=LKWYXKBTCVQGAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447379   

TargetEpidermal growth factor receptor(Human)
Jiangsu Aosaikang Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447379(CHEMBL3114699)
Affinity DataIC50: 12nMAssay Description:Inhibition of EGFR (unknown origin) after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangsu Aosaikang Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447379(CHEMBL3114699)
Affinity DataIC50: 640nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR in human KB cells incubated for 1 hr prior to EGF challenge measured after 6 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed