BDBM50447386 CHEMBL3114692

SMILES CN1CCN(C\C=C\C(=O)N2CCCOc3cc4ncnc(Nc5cccc(c5)C#C)c4cc23)CC1

InChI Key InChIKey=NNLOVRHHRCJSEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50447386   

TargetEpidermal growth factor receptor(Human)
Jiangsu Aosaikang Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447386(CHEMBL3114692)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR in human KB cells incubated for 1 hr prior to EGF challenge measured after 6 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed