BDBM50448099 CHEMBL3121331
SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1cc2cc(c(N)nc2cn1)-c1ccccc1
InChI Key InChIKey=ABEDHXMOGHHQTM-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50448099
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair