BDBM50448750 CHEMBL3127915

SMILES COc1ccc(cc1)-c1nc2cc(C)c(C)cc2n1-c1ccc2c(N)nc(N)nc2c1

InChI Key InChIKey=GIEXPBPEJBLVIC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448750   

TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

Curated by ChEMBL
LigandPNGBDBM50448750(CHEMBL3127915)
Affinity DataKi:  0.340nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Trius Therapeutics

Curated by ChEMBL
LigandPNGBDBM50448750(CHEMBL3127915)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometric analysis in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed