BDBM50449042 CHEMBL3126206::US9212144, 11 (Ex. 28)

SMILES Nc1ccc2cc(CCNCc3cccc(F)c3)ccc2n1

InChI Key InChIKey=FTQIVQZMOCKIPM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50449042   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449042(CHEMBL3126206 | US9212144, 11 (Ex. 28))
Affinity DataKi: >5.70E+3nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli using L-arginine as substrate assessed as NO production by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449042(CHEMBL3126206 | US9212144, 11 (Ex. 28))
Affinity DataKi: >5.70E+3nMpH: 7.4Assay Description:To test for enzyme inhibition, the hemoglobin capture assay was used to measure nitric oxide production. The assay was performed at 37° C. in HEPES b...More data for this Ligand-Target Pair
In DepthDetails US Patent