BDBM50449315 CHEMBL3125863

SMILES O=C(CCc1nc2ccccc2c(=O)[nH]1)Nc1ncc(Cc2ccc(F)c(F)c2)s1

InChI Key InChIKey=NSBOINOQPZJFJR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50449315   

TargetTyrosine-protein kinase JAK2(Human)
University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449315BDBM50449315(CHEMBL3125863)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of JAK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449315BDBM50449315(CHEMBL3125863)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ZAP70 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449315BDBM50449315(CHEMBL3125863)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449315BDBM50449315(CHEMBL3125863)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of Syk (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449315BDBM50449315(CHEMBL3125863)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of c-MET (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449315BDBM50449315(CHEMBL3125863)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FAK (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed