BDBM504494 2-{5-[(3-ethoxypyridin-2-yl)oxy]pyridin- 3-yl}-N-[(3R,5R)-5-fluoropiperidin-3- yl]pyrimidine-5-carboxamide, trifluoroacetate salt::US11065249, Example 7::US11471458, Example 7::US20230405002, Example 7
SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)N[C@H]1CNC[C@H](F)C1
InChI Key InChIKey=CPBXJSPVZIPJMX-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 504494
Affinity DataIC50: 42nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human DGAT2 using 14C decanoyl-CoA as a substrate pre incubated for 2 hrs followed by substrate addition measured after 40 mins by Tril...More data for this Ligand-Target Pair