BDBM50449542 CHEMBL4170787

SMILES NC1=NC2(CCN(C(=O)Nc3ccc(F)cc3)CC2)N(c2cccc(Cl)c2)C(N)=N1

InChI Key InChIKey=ZHPPVVTVVABACZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50449542   

TargetDihydrofolate reductase(Human)
University of Genoa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449542BDBM50449542(CHEMBL4170787)
Affinity DataKi:  530nMAssay Description:Binding affinity to human recombinant DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed