BDBM50451479 CHEMBL4205815

SMILES C[C@@H](N[C@H]1CC[C@H](CC1)n1cc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12)C(O)=O

InChI Key InChIKey=POLFXOSYBGYACO-RLLQIKCJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451479   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Riken Center For Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM50451479(CHEMBL4205815)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human C-terminal FLT3 ITD mutant (571 to 993 residues) after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Riken Center For Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM50451479(CHEMBL4205815)
Affinity DataIC50:  36nMAssay Description:Inhibition of recombinant human HCK SH3-SH2-KD (75 to 526 residues) after 20 mins by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed