BDBM50451553 CHEMBL3084839

SMILES N[C@H]1CC[C@H](Nc2nc(Nc3ccccc3)c3ncn(C4CCCC4)c3n2)CC1

InChI Key InChIKey=QZQGXMDLWJNGQH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50451553   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Palack£

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451553BDBM50451553(CHEMBL3084839)
Affinity DataIC50: 5nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Palack£

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451553BDBM50451553(CHEMBL3084839)
Affinity DataIC50: 7nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451553BDBM50451553(CHEMBL3084839)
Affinity DataIC50: 141nMAssay Description:Inhibition of Src-mediated dentine resorption in rabbit-osteoclast assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50451553BDBM50451553(CHEMBL3084839)
Affinity DataIC50: 196nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed