BDBM50451673 CHEMBL4202432

SMILES CC(C)N1CCN(Cc2cnc(Nc3cc(ncn3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)cn2)CC1

InChI Key InChIKey=HTNZLGGHWZIRJC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50451673   

TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Shanghai Haihe Pharmaceutial

Curated by ChEMBL
LigandPNGBDBM50451673(CHEMBL4202432)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of CDK4 (unknown origin) using U-light as substrate preincubated for 1 hr followed by EDTA addition measured after 1 hr by LANCE Ultra kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Shanghai Haihe Pharmaceutial

Curated by ChEMBL
LigandPNGBDBM50451673(CHEMBL4202432)
Affinity DataIC50:  97nMAssay Description:Inhibition of CDK1 (unknown origin) using U-light as substrate preincubated for 1 hr followed by EDTA addition measured after 1 hr by LANCE Ultra kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Shanghai Haihe Pharmaceutial

Curated by ChEMBL
LigandPNGBDBM50451673(CHEMBL4202432)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of CDK6 (unknown origin) using U-light as substrate preincubated for 1 hr followed by EDTA addition measured after 1 hr by LANCE Ultra kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed