BDBM50452198 CHEMBL4207234::US10647727, Example 8

SMILES Cn1ncc2c(NC(C)(C)c3ccc(cc3)C(F)(F)F)nc(Cl)nc12

InChI Key InChIKey=DYMCMWGNKPVBTB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452198   

TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50452198(CHEMBL4207234 | US10647727, Example 8)
Affinity DataKi:  642nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50452198(CHEMBL4207234 | US10647727, Example 8)
Affinity DataKi:  642nMAssay Description:Binding affinity to PDE2 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed