BDBM50453922 CHEMBL4218476

SMILES Cl.COc1ccccc1CCN1CCC(CCc2cccc(OCCF)c2)CC1

InChI Key InChIKey=UIQIVXSXFCHFKX-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50453922   

TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50453922(CHEMBL4218476)
Affinity DataKi:  61nMAssay Description:Inhibition of [3H]dopamine uptake at VMAT2 in rat striatal synaptic vesicles by scintillation spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50453922(CHEMBL4218476)
Affinity DataKi:  470nMAssay Description:Inhibition of [3H]serotonin uptake at SERT in rat striatal synaptosomes preincubated for 5 mins followed by radioligand addition measured after 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50453922(CHEMBL4218476)
Affinity DataKi:  4.79E+3nMAssay Description:Inhibition of [3H]dopamine uptake at dopamine transporter in rat striatal synaptosomes preincubated for 5 mins followed by radioligand addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50453922(CHEMBL4218476)
Affinity DataIC50:  800nMAssay Description:Displacement of [3H]Dofetilide from human ERG expressed in HEK293 cells after 60 mins by scintillation spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed