BDBM50454220 CHEMBL4211454

SMILES Fc1cccc(-n2cnc3c(NCc4nc5c(F)c(F)ccc5[nH]4)nc(N4CCOCC4)nc32)c1

InChI Key InChIKey=CEBMEQPREMCWOL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50454220   

TargetCasein kinase I isoform delta(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454220BDBM50454220(CHEMBL4211454)
Affinity DataIC50: 44nMAssay Description:Inhibition of CK1delta (unknown origin) using Light-TopoIla(Thr1342) peptide as substrate incubated for 10 mins in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCasein kinase I isoform delta(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454220BDBM50454220(CHEMBL4211454)
Affinity DataIC50: 44nMAssay Description:Inhibition of CK1 delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCasein kinase I isoform delta(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454220BDBM50454220(CHEMBL4211454)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CK1delta expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr1342...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 12(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454220BDBM50454220(CHEMBL4211454)
Affinity DataIC50: 86nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCasein kinase I isoform epsilon(Human)
Scripps Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454220BDBM50454220(CHEMBL4211454)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCasein kinase I isoform epsilon(Human)
Scripps Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454220BDBM50454220(CHEMBL4211454)
Affinity DataIC50: 260nMAssay Description:Inhibition of CK1epsilon (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCasein kinase I isoform epsilon(Human)
Scripps Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454220BDBM50454220(CHEMBL4211454)
Affinity DataIC50: 260nMAssay Description:Inhibition of CK1 epsilon (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed