BDBM50454320 CHEMBL4217516

SMILES COc1c(O)cc2oc3cc(O)c(CCC(C)(C)O)c(O)c3c(=O)c2c1CC=C(C)C

InChI Key InChIKey=WJCMDIAPJJTACW-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50454320   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454320BDBM50454320(CHEMBL4217516)
Affinity DataKi:  2.29E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454320BDBM50454320(CHEMBL4217516)
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProbable maltase-glucoamylase 2(Human)
Gyeongsang National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454320BDBM50454320(CHEMBL4217516)
Affinity DataKi:  2.51E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProbable maltase-glucoamylase 2(Human)
Gyeongsang National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454320BDBM50454320(CHEMBL4217516)
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate measured for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed