BDBM50455534 CHEMBL4213768

SMILES CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(OCC(=O)NCc2ccccc2)cc1

InChI Key InChIKey=YQNDSSWLPSRYLJ-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50455534   

TargetAdenosine receptor A2b(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50455534(CHEMBL4213768)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]PSB-603 from recombinant human adenosine A2B receptor expressed in CHO cell membranes after 75 mins by liquid scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50455534(CHEMBL4213768)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50455534(CHEMBL4213768)
Affinity DataKi:  266nMAssay Description:Displacement of [3H]PSB-11 from recombinant human adenosine A3 receptor expressed in CHO cell membranes after 45 mins by liquid scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50455534(CHEMBL4213768)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatal membranes after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50455534(CHEMBL4213768)
Affinity DataIC50:  135nMAssay Description:Antagonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as inhibition of NECA-induced cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed