BDBM50455956 CHEMBL5271803

SMILES CN(C)CCn1cccc1\C=N\NC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1

InChI Key InChIKey=SFQUNUNAFYNODH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50455956   

TargetEpidermal growth factor receptor(Human)
School of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50455956(CHEMBL5271803)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
School of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50455956(CHEMBL5271803)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed