BDBM50455957 CHEMBL5289358

SMILES Fc1ccc(Nc2ncnc3cc(O[C@H]4CCOC4)c(NC(=O)N\N=C\c4cnc(nc4)N4CCCC4)cc23)cc1Cl

InChI Key InChIKey=DIMLJOPEJOMHIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50455957   

TargetEpidermal growth factor receptor(Human)
School of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50455957(CHEMBL5289358)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of EGFR (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
School of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50455957(CHEMBL5289358)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed