BDBM50456363 CHEMBL4210737

SMILES C[C@]12CC[C@H]3[C@@H](C[C@@H]4C[C@@]45C[C@@H](O)CC[C@]35C)[C@@H]1CC=C2c1cccnc1

InChI Key InChIKey=SGBMHXUDAZFBJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50456363   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50456363BDBM50456363(CHEMBL4210737)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of C-terminal His-tagged recombinant human CYP17A1delta19H mutant expressed in Escherichia coli DH5alpha assessed as decrease in progester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSteroid 21-hydroxylase(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50456363BDBM50456363(CHEMBL4210737)
Affinity DataIC50: 42nMAssay Description:Inhibition of C-terminal His-tagged recombinant human CYP21A2deltaH mutant expressed in Escherichia coli DH5alpha assessed as decrease in progesteron...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed