BDBM50457445 CHEMBL4212818
SMILES Clc1ccc(cc1)C(=O)Nc1c(nc2ccccn12)-c1cccs1
InChI Key InChIKey=AZKMWHRDICVYEI-UHFFFAOYSA-N
Data 5 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50457445
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 860nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha1beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 970nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha4beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 980nMAssay Description:Positive allosteric modulation of human recombinant alpha4beta1delta GABAA receptor expressed in delta-HEK cells assessed as potentiation of GABA-ind...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 2.29E+3nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 2.44E+3nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair