BDBM50457788 CHEMBL4209555

SMILES CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2ccccc2)c1F

InChI Key InChIKey=ZBYVHRGXNKMPDO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50457788   

TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50457788(CHEMBL4209555)
Affinity DataIC50:  40nMAssay Description:Inhibition of full-length GST-tagged mouse BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed