BDBM50458004 CHEMBL4210397

SMILES [#6]-[#6]\[#6](=[#6](\c1ccc(-[#8]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1)-c1ccc(-[#8]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1)-c1cccc(c1)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](-[#7])=O

InChI Key InChIKey=RYJUKWVVXKCKAY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50458004   

TargetProteasome subunit beta type-5(Human)
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458004(CHEMBL4210397)
Affinity DataIC50: 890nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458004(CHEMBL4210397)
Affinity DataIC50: 990nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458004(CHEMBL4210397)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome using Boc-LRR-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458004(CHEMBL4210397)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458004(CHEMBL4210397)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of PGPH activity of human 26S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458004(CHEMBL4210397)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of trypsin-like activity of human 26S proteasome using Boc-LRR-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed