BDBM50458251 CHEMBL4215380

SMILES CN(Cc1cc(ncn1)N1CCN(C)CC1)[C@@H]1CCCc2cccnc12

InChI Key InChIKey=LPTRCGOYHAYNCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50458251   

TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458251(CHEMBL4215380)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at CXCR4 in human CD4+ T cells assessed as inhibition of CXCL12-mediated cytosolic calcium level preincubated with compounds foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458251(CHEMBL4215380)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed