BDBM50458587 CHEMBL4207292

SMILES C=CC(=O)N1CC[C@]2(C1)C[C@H](n1c(NC(=O)c3ccc(-c4ccnc(N)c4)s3)nc3ccccc31)C2

InChI Key InChIKey=WPFZWTKQXNTKQJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50458587   

TargetTyrosine-protein kinase TXK(Human)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458587BDBM50458587(CHEMBL4207292)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458587BDBM50458587(CHEMBL4207292)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of TEC (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458587BDBM50458587(CHEMBL4207292)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of BTK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458587BDBM50458587(CHEMBL4207292)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of ITK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed