BDBM50458668 CHEMBL4217503

SMILES OC(=O)CCC(=O)N(C1CC1)C1C2CCCC2N(C(=O)c2ccccc2)c2ccccc12

InChI Key InChIKey=OSRNONJISPOSIJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50458668   

TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458668(CHEMBL4217503)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458668(CHEMBL4217503)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced intracellular c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed