BDBM50458690 CHEMBL4205047

SMILES [H][C@@]12CCC[C@]1([H])N(C(=O)c1ccc(SC(F)(F)F)cc1)c1ccc(F)cc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O

InChI Key InChIKey=SUSDXYWNEJZUPP-FZOAFFARSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50458690   

TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458690(CHEMBL4205047)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458690(CHEMBL4205047)
Affinity DataIC50:  2.40nMAssay Description:Antagonist activity at human CRTh2 expressed in CHOK1 cells assessed as inhibition of PGD2-induced beta-arrestin recruitment incubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458690(CHEMBL4205047)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced intracellular c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed