BDBM50458927 CHEMBL4214637
SMILES Clc1cccc(COc2cccc3onc(Nc4cccnc4)c23)c1
InChI Key InChIKey=NDSZUDJYEHKGLF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50458927
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Human)
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair