BDBM50459026 CHEMBL4214902::US10611730, Example 31
SMILES FC(F)(F)Oc1cccc(Cl)c1-c1ccc2[nH]c(=O)[nH]c2c1
InChI Key InChIKey=COBXSLRIXGQVGS-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50459026
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Affinity DataIC50: 6.31nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma2 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair