BDBM50459032 CHEMBL4215352

SMILES Cc1cc(cc2CC(=O)Nc12)-c1c(Cl)cncc1OC(F)F

InChI Key InChIKey=HNSMBMPEJNXIBA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50459032   

TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50459032(CHEMBL4215352)
Affinity DataIC50: <1.00E+4nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma2 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50459032(CHEMBL4215352)
Affinity DataIC50:  7.90nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed