BDBM50459175 CHEMBL4204687

SMILES CN1CCN(CCNc2cc(O)c3c(c2)oc2c(Cc4ccc5OCOc5c4)[nH]c(-c4nccs4)c2c3=O)CC1

InChI Key InChIKey=SKXNASBNWUVYCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50459175   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50459175(CHEMBL4204687)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of human PDE5A1 catalytic domain (535 to 860 residues) expressed in Escherichia coli BL21 using 3H-cGMP as substrate after 15 mins by liqu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed