BDBM50459404 CHEMBL4205046

SMILES Cc1ccn(n1)C(=O)Nc1ccc(C(=O)N2CCCCc3ccccc23)c(Cl)c1

InChI Key InChIKey=WLSCYTZXIQSDLZ-UHFFFAOYSA-N

Data  3 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50459404   

TargetVasopressin V2 receptor(Human)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50459404(CHEMBL4205046)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-AVP from human V2 receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetVasopressin V1a receptor(Human)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50459404(CHEMBL4205046)
Affinity DataKi:  239nMAssay Description:Displacement of [3H]-AVP from human V1A receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetOxytocin receptor(Human)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50459404(CHEMBL4205046)
Affinity DataKi:  325nMAssay Description:Displacement of [3H]-AVP from human OXR receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetOxytocin receptor(Human)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50459404(CHEMBL4205046)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at OXR receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50459404(CHEMBL4205046)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human V2 receptor expressed in human HeLa cells assessed as cAMP accumulation incubated for 10 mins by radioimmunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetVasopressin V1b receptor(Human)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50459404(CHEMBL4205046)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human V1B receptor expressed in human HeLa cells assessed as inhibition of AVP-induced cAMP accumulation incubated for 10 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50459404(CHEMBL4205046)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human V2 receptor expressed in human HeLa cells assessed as inhibition of AVP-induced cAMP accumulation incubated for 10 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetVasopressin V1a receptor(Human)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50459404(CHEMBL4205046)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human V1A receptor expressed in human HeLa cells assessed as inhibition of AVP-induced cAMP accumulation incubated for 10 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed