BDBM50459416 CHEMBL4216473

SMILES COCCOc1cc(F)c2c(Nc3ccc(NC(=O)Cn4cc(nn4)C(C)C)cc3)ncnc2c1

InChI Key InChIKey=FLJOFQUXYAWOPE-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50459416   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50459416(CHEMBL4216473)Copy SMILESCopy InChI

Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails ArticlePubMed
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TargetPlatelet-derived growth factor receptor alpha(Human)
Jinan University

Curated by ChEMBL

LigandBDBM50459416(CHEMBL4216473)Copy SMILESCopy InChI

Affinity DataIC50:  1nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails PubMed
Copy BDB DOI
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TargetMast/stem cell growth factor receptor Kit(Human)
Jinan University

Curated by ChEMBL

LigandBDBM50459416(CHEMBL4216473)Copy SMILESCopy InChI

Affinity DataIC50:  3nMAssay Description:Inhibition of wild type KIT (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI
Copy reaction URL