BDBM50459570 CHEMBL4217295

SMILES Nc1nc(Nc2ccc(cc2)N2CCOCC2)nc(n1)-c1cccc(N2CCc3cc(cc(F)c3C2=O)C2CC2)c1CO

InChI Key InChIKey=YFAWRQMBLMUWKC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50459570   

TargetTyrosine-protein kinase BTK(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50459570(CHEMBL4217295)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of N-terminal DYKDDDDK tagged biotinylated unactivated human recombinant BTK using FITC-labeled Srctide peptide substrate by by mobility s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50459570(CHEMBL4217295)
Affinity DataIC50: 70nMAssay Description:Inhibition of N-terminal DYKDDDDK tagged biotinylated activated human recombinant BTK using FITC-labeled Srctide peptide substrate by mobility shift ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed