BDBM50460389 CHEMBL4226907

SMILES Fc1ccc(\C=N\NC(=O)N2CCc3ncnc(Nc4cccc(Br)c4)c3C2)c(Cl)c1

InChI Key InChIKey=ZKTBVCBTPKBWDX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50460389   

TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50460389(CHEMBL4226907)
Affinity DataIC50: 18nMAssay Description:Inhibition of EGFR (unknown origin) using peptide substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50460389(CHEMBL4226907)
Affinity DataIC50: 133nMAssay Description:Inhibition of VEGFR2 (unknown origin) using peptide substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50460389(CHEMBL4226907)
Affinity DataIC50: 940nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) using peptide substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed