BDBM50460390 CHEMBL4228120

SMILES Fc1cc(Cl)c(\C=N\NC(=O)N2CCc3ncnc(Nc4ccc(F)c(Cl)c4)c3C2)cc1F

InChI Key InChIKey=CUYZENZHIGMEAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50460390   

TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50460390(CHEMBL4228120)
Affinity DataIC50: 42nMAssay Description:Inhibition of EGFR (unknown origin) using peptide substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50460390(CHEMBL4228120)
Affinity DataIC50: 170nMAssay Description:Inhibition of VEGFR2 (unknown origin) using peptide substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed