BDBM50460560 CHEMBL4225871

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C2CC2)c(Cc2ccc3CCc3c2)c1

InChI Key InChIKey=RDPDCLWTCNJXKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50460560   

TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460560(CHEMBL4225871)
Affinity DataIC50: 5nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460560(CHEMBL4225871)
Affinity DataIC50: 32nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed